CBD and other cannabinoids attach to specific receptors in the body found within what is referred to as the endocannabinoid system. In fact, up until recently, scientists didn’t know that these cannabinoids are actually naturally produced in humans and most animals. Some researchers speculate that an endocannabinoid deficiency may be the cause of many disorders and conditions. When CBD is introduced into the body, it binds to receptor cells called CB1 and CB2 receptors.
Our bodies are thought to produce endocannabinoids by the billions every day. “We always thought the ‘runner’s high’ was due to the release of dopamine and endorphins. But now we know the euphoria is also from an endocannabinoid called anandamide,” its name derived from the Sanskrit word for bliss, says Joseph Maroon, MD, clinical professor and vice chairman of neurosurgery at the University of Pittsburgh Medical Center. We produce these natural chemicals all day, but they fade quickly because enzymes pop up to destroy them. That’s where CBD comes in: By blocking these enzymes, CBD allows the beneficial compounds to linger.

Current studies, including one carried out by the UC San Diego School of Medicine, are looking into how the endocannabinoid system may be linked to reducing symptoms associated with autism. This is due to its role in social reward responsivity, neural development and circadian rhythm and anxiety regulation – all of which are often affected by autism. (52)


Cannabis has always been a popular form of treatment for a variety of medical conditions, but in the 1930’s growing concerns about the dangers of marijuana abuse led to cannabinoids being banned. A century has past and despite all efforts from cannabis enthusiasts through social media channels and online media, cannabis is still classed as a schedule 1 drug.
CBD oil has been scientifically proven to reduce stress. It combats stress both psychologically and physically. Psychologically, it levels out your brains cortisol levels. Cortisol is the stress hormone, and high levels are associated with chronic depression, anxiety, and low immune function. Whenever you get stressed out, your body produces excessive amounts of the chemical.

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The increased activity of the pancreas in an attempt to secrete additional insulin can cause inflammation throughout the gland. That chronic inflammation can actually destroy the beta cells which are the sites that secrete insulin. This downward spiral diminishes the body’s ability to make insulin at all – a dangerous path that can lead to diabetes.
‘CBD has proven anti-anxiety effects and may be helpful in depression, based on anecdotal reports,’ says Dr Gordon. ‘I use high CBD prescription cannabis medicine products as part of a mental health protocol with my patients suffering with anxiety and depression. The antidepressant effects of CBD have been shown in animal models, but we now need large, depression-specific studies in humans as the next step.’

‘CBD has proven anti-anxiety effects and may be helpful in depression, based on anecdotal reports,’ says Dr Gordon. ‘I use high CBD prescription cannabis medicine products as part of a mental health protocol with my patients suffering with anxiety and depression. The antidepressant effects of CBD have been shown in animal models, but we now need large, depression-specific studies in humans as the next step.’


Alicia Salazar, a New York state board certified health coach, uses CBD with her clients to maximize their health outcomes. “I don’t look at CBD as a magic bullet for weight loss,” she said. “But CBD along with a healthy diet – one that contains healthy fats, whole grains, grass-fed meat and dairy, and plenty of greens, without processed foods and sugar – sets the tone for a healthy weight. And for some, that can naturally include weight loss.”

ADHD, or attention deficit disorder, with or without hyperactivity, is often first noticed and diagnosed in school-aged children (it is the most commonly diagnosed neurodevelopmental disorder of childhood). Many sufferers must learn to adapt to difficulties in paying attention, remembering seemingly simple tasks, being over-compulsive and more, over the long term. (44)


The immediate and powerful effects of THC are explained because of the special affinity it has with the CB1 type receptors, which mediate crucial processes in the brain. The less prominent (but no less important) action of CBD was explained, at least for a while, by hypothesizing that it binds to CB2 type receptors, hence its more diffuse manner of exercising changes in the body. Early on, the antipsychotic effects of cannabidiol were observed, an aspect which seemed to be in consonance with this initial hypothesis.
The current trend in the cannabis-related area of research started in the late sixties and early seventies when products derived from cannabis (especially marijuana) were placed on the list of controlled substances in the US, under the Nixon administration. This move was retroactively interpreted as being part of the conservative reaction to the liberalizing spirit of the sixties.
CBD hemp oil is the product derived from the hemp plant, which is high in CBD (cannabidiol) and low in THC (tetrahydrocannabinol). This oil has received a large amount of attention in recent years, due to the growing wave of marijuana legislation and debate in many countries, including the United States. While cannabis and smoking marijuana (which often has a high level of the psychotropic compound THC) is still illegal in many places, as more is being learned about CBD, and its potential effects on health, it is becoming more and more accepted as a legal and safe remedy for a wide variety of health conditions. Since it has a minimal amount of the psychotropic compound THC, use of this oil does not result in a traditional “high”, so its effects are generally considered therapeutic, not mind-altering.

Hemp oil does have a number of uses and is often marketed as a cooking oil or a product that is good for moisturizing the skin. It is also used in the production of certain soaps, shampoos, and foods. It is also a basic ingredient for bio-fuel and even a more sustainable form of plastic. Hemp has been cultivated and used for roughly 10,000 years, and it definitely has useful purposes. However, a lack of cannabinoids, namely CBD, means that it has little therapeutic value.


‘CBD has proven anti-anxiety effects and may be helpful in depression, based on anecdotal reports,’ says Dr Gordon. ‘I use high CBD prescription cannabis medicine products as part of a mental health protocol with my patients suffering with anxiety and depression. The antidepressant effects of CBD have been shown in animal models, but we now need large, depression-specific studies in humans as the next step.’

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Pure Hemp Botanicals has created a soothing tea made from whole-plant ingredients. The product is packaged locally and is cruelty-free and vegan. It includes the flavors of hibiscus and apple to reduce the hemp aftertaste. The hemp used to create this oil has been organically grown, and the tea contains full-spectrum plant terpenes that are entirely natural. It is also caffeine free.

Due to the uniqueness of everyone’s endocannabinoid system, CBD does not affect any two people the same way. There are a host of factors that influence its efficacy, including genetics, previous history of use, general health, weight, ethnicity and so on. Therefore, while one person may find that 15 mg of CBD a day works wonders for suppressing appetite and boosting weight loss, another may require up to 100 mg (or more) in order to achieve the same results (in fact, they may not experience any results at all).

CBD oil has been scientifically proven to reduce stress. It combats stress both psychologically and physically. Psychologically, it levels out your brains cortisol levels. Cortisol is the stress hormone, and high levels are associated with chronic depression, anxiety, and low immune function. Whenever you get stressed out, your body produces excessive amounts of the chemical.

People who experience psychosis may produce too much or even too little cannabinoids (from overactive dopamine receptors). CBD is milder than our internal cannabinoids and helps to re-establish a balance of cannabinoids in the brain. CBD also helps lower inflammation, which is often increased in schizophrenia. THC, on the other hand, is stronger than our internal cannabinoids (anandamide and 2-AG), this way potentially triggering psychosis [46, 48].

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